Description
Hepatitis B core antigen (HBcAg) is a single polypeptide with a molecular weight of 18848u.
HBcAg plays an important role in HBV infection.
It can reflect the presence of Dane particles in serum and the replication of HBV in liver, and can cooperate and complement with other HBV serological markers.
Only because its antibody has a strong affinity and can rapidly combine with HBcAg in serum to form immune complexes, it is difficult to measure free HBcAg in serum.
Double antibody sandwich ELISA is commonly used to detect HBcAg